RAMAN SPECTROSCOPIC INVESTIGATION OF THE EFFECT OF ELECTRICAL STIMULATION ON DESTROYING LIPID MEMBRANE OF VIRUSES

Abstract

In this study, the destruction of the lipid membrane of viruses by electrical simulation was investigated by molecular modeling. Since it is well known that soap directly attacks the virus by disrupting its the lipid bilayer membrane, the formation of soap by electrical simulations of human body fluids were modeled, using saline and oil added saline solutions. Oil was used as a model for lipid membrane and molecular structural alterations were followed by using Raman spectroscopy. The results indicated that when electrical simulations were performed by using square wave dc current 10V for 10 m duration, the acidic saline environment converted to basic environment, which destroyed the added oil by formation of soap.